Updated on 2025/03/27

写真a

 
Ninomiya Daisuke
 
Organization
Graduate School of Medicine Program for Medical Sciences Assistant Professor
Title
Assistant Professor
Contact information
メールアドレス
External link

Degree

  • 学士（医学） ( 自治医科大学 )

Papers

  • Thigh circumference and handgrip strength are significantly associated with all-cause mortality: findings from a study on Japanese community-dwelling persons.

    Kawamoto Ryuichi,Kikuchi Asuka,Akase Taichi,Ninomiya Daisuke,Kumagi Teru

    European geriatric medicine   12 ( 6 )   1191 - 1200   2021.12

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    In addition to playing a critical role in cardiovascular health, muscle mass and strength independently impact aging-related health outcomes in adults. There are limited predictive data for all-cause mortality, particularly for community-dwelling persons

    DOI： 10.1007/s41999-021-00515-2

  • Low density lipoprotein cholesterol and all-cause mortality rate: findings from a study on Japanese community-dwelling persons.

    Kawamoto Ryuichi,Kikuchi Asuka,Akase Taichi,Ninomiya Daisuke,Kumagi Teru

    Lipids in health and disease   20 ( 1 )   105   2021.9

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    Low-density lipoprotein cholesterol (LDL-C) independently impacts aging-related health outcomes and plays a critical role in cardiovascular diseases (CVDs). However, there are limited predictive data on all-cause mortality, especially for the Japanese com

    DOI： 10.1186/s12944-021-01533-6

  • 地域医療学講座(総合診療科)における最近の研究紹介

    川本 龍一, 菊池 明日香, 赤瀬 太一, 二宮 大輔, 徳本 良雄, 熊木 天児

    愛媛医学   40 ( 2 )   61 - 69   2021.6

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    Language：Japanese   Publisher：愛媛医学会  

  • Alcohol consumption and serum uric acid are synergistically associated with renal dysfunction among community-dwelling persons.

    Kawamoto Ryuichi,Kikuchi Asuka,Akase Taichi,Ninomiya Daisuke,Tokumoto Yoshio,Kumagi Teru

    Journal of clinical laboratory analysis   35 ( 6 )   e23812   2021.6

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    Serum uric acid (SUA) is a key risk factor contributing to renal failure, a serious public health problem. However, few studies have examined whether the interactive relationship between alcohol consumption and SUA is independently associated with the est

    DOI： 10.1002/jcla.23812

  • 地域在住者において中等度のアルコール摂取量は高尿酸血症による腎機能障害に保護的効果がみられる

    川本 龍一, 二宮 大輔, 菊池 明日香, 和田 悠

    糖尿病   64 ( Suppl.1 )   I - 20-6   2021.5

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    Language：Japanese   Publisher：(一社)日本糖尿病学会  

  • 地域在住者において握力は血清尿酸による腎機能低下に対して保護効果を有する

    川本 龍一, 二宮 大輔, 楠木 智

    日本老年医学会雑誌   58 ( Suppl. )   190   2021.5

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  • Clubbed Digits Presumably Caused by Lubiprostone.

    Kawamoto Ryuichi,Kikuchi Asuka,Ninomiya Daisuke,Kumagi Teru

    Internal medicine (Tokyo, Japan)   60 ( 15 )   2499 - 2502   2021

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    Digital clubbing has been regarded as an important sign in medicine. A 33-year-old woman with no history of hepatic, pulmonary, or malignant disease was referred to our hospital. She had been taking lubiprostone every day for three years for constipation.

    DOI： 10.2169/internalmedicine.6104-20

  • A case of laryngopharyngeal reflux-associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay.

    Kikuchi Asuka,Kawamoto Ryuichi,Mizumoto Junki,Akase Taichi,Ninomiya Daisuke,Kumagi Teru

    Journal of general and family medicine   21 ( 6 )   258 - 260   2020.11

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    A 62-year-old woman presented with a dry cough lasting 18 months. She had previously been examined by multiple doctors, but no abnormalities were observed. Several medications such as rabeprazole and inhaled corticosteroids were administered as test treat

    DOI： 10.1002/jgf2.348

  • リウマチ性多発筋痛症の経過観察中にMALTリンパ腫を合併した1例

    菊池 明日香, 二宮 大輔, 古川 慎哉, 熊木 天児, 川本 龍一

    日本老年医学会雑誌   57 ( 4 )   519 - 520   2020.10

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  • 尿酸と尿酸変化はメタボリックシンドロームの独立予測因子である

    川本 龍一, 二宮 大輔

    糖尿病   63 ( Suppl.1 )   S - 279   2020.8

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  • Increased body mass index above the upper normal limit is significantly associated with renal dysfunction among community-dwelling persons.

    Kawamoto Ryuichi,Kikuchi Asuka,Akase Taichi,Ninomiya Daisuke,Kasai Yoshihisa,Ohtsuka Nobuyuki,Kumagi Teru

    International urology and nephrology   52 ( 8 )   1533 - 1541   2020.8

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    Body mass index (BMI) is a simple index of weight-to-height that is commonly used to classify people as underweight, overweight or obesity, and high BMI has been clearly linked to increased risk of illness in adults. However, few studies have examined the

    DOI： 10.1007/s11255-020-02501-2

  • 「ウエスト/身長比」はメタボリックシンドロームの優れた予測因子である

    川本 龍一, 二宮 大輔, 菊池 明日香, 赤瀬 太一

    日本老年医学会雑誌   57 ( Suppl. )   113 - 114   2020.7

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  • The effect of short-term exposure to rural interprofessional work on medical students.

    Kawamoto Ryuichi,Ninomiya Daisuke,Akase Taichi,Kikuchi Asuka,Kumagi Teru

    International journal of medical education   11   136 - 137   2020.6

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    DOI： 10.5116/ijme.5eb6.81cb

  • Interactive association of baseline and changes in serum uric acid on renal dysfunction among community-dwelling persons.

    Kawamoto Ryuichi,Ninomiya Daisuke,Akase Taichi,Kikuchi Asuka,Kumagi Teru

    Journal of clinical laboratory analysis   34 ( 5 )   e23166   2020.5

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    Chronic kidney disease (CKD) is a major public health concern. Baseline serum uric acid (SUA) levels were independently associated with incident renal dysfunction, but whether baseline and changes in SUA produce an interactive effect on renal dysfunction

    DOI： 10.1002/jcla.23166

  • High serum uric acid within the normal range is a useful predictor of hypertension among Japanese community-dwelling elderly women.

    Kawamoto Ryuichi,Ninomiya Daisuke,Akase Taichi,Asuka Kikuchi,Kumagi Teru

    Clinical hypertension   26   20   2020

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    The risk associated with serum uric acid (SUA) levels when within the normal range is unknown. This study aims to examine whether SUA within the normal range is a predictor of hypertension.The subjects comprised 704 men aged 71 ± 9 (mean ± standard deviat

    DOI： 10.1186/s40885-020-00155-x

  • Metabolic syndrome is a predictor of decreased renal function among community-dwelling middle-aged and elderly Japanese.

    Kawamoto Ryuichi,Akase Taichi,Ninomiya Daisuke,Kumagi Teru,Kikuchi Asuka

    International urology and nephrology   51 ( 12 )   2285 - 2294   2019.12

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    Metabolic syndrome (MetS) is increasing worldwide with the continuous increase in obesity prevalence. Chronic kidney disease (CKD) is also a major public health problem, but there is controversy over whether baseline MetS is a predictor of decreased renal

    DOI： 10.1007/s11255-019-02320-0

  • 地域住人女性においてベースライン時尿酸とその後変化は、メタボリックシンドロームの発症と関係している

    川本 龍一, 二宮 大輔, 菊池 明日香, 赤瀬 太一, 古川 慎哉, 熊木 天児

    日本病院総合診療医学会雑誌   15 ( 6 )   580   2019.11

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  • 尿酸・クレアチニン比はメタボリックシンドロームの独立予測因子である

    川本 龍一, 二宮 大輔, 楠木 智

    日本老年医学会雑誌   56 ( Suppl. )   179   2019.5

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  • 糖尿病患者における好中球・リンパ球比と早期腎機能障害およびアルブミン尿との関係

    川本 龍一, 二宮 大輔

    糖尿病   62 ( Suppl.1 )   S - 341   2019.4

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  • Association of neutrophil-to-lymphocyte ratio with early renal dysfunction and albuminuria among diabetic patients.

    Kawamoto Ryuichi,Ninomiya Daisuke,Kikuchi Asuka,Akase Taichi,Kasai Yoshihisa,Kusunoki Tomo,Ohtsuka Nobuyuki,Kumagi Teru

    International urology and nephrology   51 ( 3 )   483 - 490   2019.3

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    Neutrophil-to-lymphocyte ratio (NLR) was widely studied as a prognostic marker in various medical and surgical specialties, but its significance in diabetic kidney disease is not yet established.The subjects comprised 199 men aged 73 ± 11 (mean ± standard

    DOI： 10.1007/s11255-018-02065-2

  • Serum Uric Acid to Creatinine Ratio Independently Predicts Incident Metabolic Syndrome Among Community-Dwelling Persons.

    Kawamoto Ryuichi,Ninomiya Daisuke,Akase Taichi,Kikuchi Asuka,Kasai Yoshihisa,Kusunoki Tomo,Ohtsuka Nobuyuki,Kumagi Teru

    Metabolic syndrome and related disorders   17 ( 2 )   81 - 89   2019.3

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    Metabolic syndrome (MetS) is related to the increased risk of major cardiovascular disease. The link between high serum uric acid (SUA) and creatinine (Cr) levels is causally related to MetS and its components. However, whether renal function-normalized S

    DOI： 10.1089/met.2018.0055

  • 地域在住者の血清尿酸値と総ビリルビン値は腎機能に交互作用的に関係している

    川本 龍一, 二宮 大輔, 赤瀬 太一, 千崎 健佑, 笠井 誉久, 楠木 智, 大塚 伸之, 熊木 天児

    日本老年医学会雑誌   55 ( Suppl. )   157   2018.5

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  • 地域在住の中高齢者において軽度に上昇した血清総ビリルビン値はヘモグロビンA1cと負に関係する

    川本 龍一, 二宮 大輔, 熊木 天児

    糖尿病   61 ( Suppl.1 )   S - 295   2018.4

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  • Bacteriological testing and recurrence prevention efforts in the diagnosis and treatment of nursing- and healthcare-associated pneumonia and aspiration pneumonia: A questionnaire survey of hospitals across Japan.

    Kenzaka Tsuneaki,Kumabe Ayako,Kosami Koki,Matsuoka Yasufumi,Minami Kensuke,Ninomiya Daisuke,Noda Ayako,Yahata Shinsuke

    Respiratory investigation   56 ( 2 )   150 - 157   2018.3

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    Clinical practice guidelines for nursing- and healthcare-associated pneumonia (NHCAP) were developed for pneumonia caused by drug-resistant bacteria and pneumonia in elderly patients, particularly aspiration pneumonia. The identification of pathogenic bac

    DOI： 10.1016/j.resinv.2017.12.005

  • 中高年女性においてAlanine aminotransferaseとTotal bilirubinはメタボリックシンドロームと相乗効果的に関係している

    川本 龍一, 二宮 大輔, 千崎 健佑, 楠木 智, 大塚 伸之, 熊木 天児

    日本内科学会雑誌   107 ( Suppl. )   163   2018.2

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  • Interaction between body mass index and serum uric acid in relation to blood pressure in community-dwelling Japanese men.

    Kawamoto Ryuichi,Ninomiya Daisuke,Senzaki Kensuke,Kumagi Teru

    Clinical hypertension   24   1   2018

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    Few data is available on the association between body mass index (BMI), serum uric acid (SUA) levels and blood pressure (BP) categories in the disease continuum, when efforts for its prevention may be applicable.We performed a cross-sectional study to exa

    DOI： 10.1186/s40885-018-0087-3

  • Baseline and changes in serum uric acid independently predict glucose control among community-dwelling women.

    Kawamoto Ryuichi,Ninomiya Daisuke,Kikuchi Asuka,Akase Taichi,Kumagi Teru

    Diabetology & metabolic syndrome   10   55   2018

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    Elevated serum uric acid (SUA) levels are associated with glucose control. However, whether baseline and changes in SUA predict long-term follow-up glucose control [e.g., glycated hemoglobin (HbA1c)] remains unclear.The subjects comprised 393 women aged 7

    DOI： 10.1186/s13098-018-0356-z

  • Alanine Aminotransferase and Total Bilirubin Are Synergistically Associated with Metabolic Syndrome Among Middle-Aged and Elderly Japanese Women.

    Kawamoto Ryuichi,Ninomiya Daisuke,Senzaki Kensuke,Kumagi Teru

    Metabolic syndrome and related disorders   15 ( 8 )   407 - 415   2017.10

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    Metabolic syndrome (MetS) is associated with an increased risk of major cardiovascular events. Alanine aminotransferase (ALT) at high levels and total bilirubin (T-BiL) at low levels were oxidative potentials, but it was uncertain whether ALT and T-BiL ha

    DOI： 10.1089/met.2017.0064

  • Interactive association of serum uric acid and total bilirubin with renal dysfunction among community-dwelling subjects.

    Kawamoto Ryuichi,Ninomiya Daisuke,Senzaki Kensuke,Kasai Yoshihisa,Kusunoki Tomo,Ohtsuka Nobuyuki,Kumagi Teru

    International urology and nephrology   49 ( 8 )   1439 - 1446   2017.8

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    Chronic kidney disease is a major public health concern. Serum uric acid (SUA) at high levels was oxidative stress agents, and total bilirubin (T-BiL) at mildly increased levels was potent antioxidants, but whether SUA and T-BiL produce an additive intera

    DOI： 10.1007/s11255-017-1633-8

  • Physicians' opinions regarding the criteria for resuming oral intake after aspiration pneumonia: A questionnaire survey and cluster analysis of hospitals across Japan.

    Kenzaka Tsuneaki,Kumabe Ayako,Kosami Koki,Matsuoka Yasufumi,Minami Kensuke,Ninomiya Daisuke,Noda Ayako,Okayama Masanobu

    Geriatrics & gerontology international   17 ( 5 )   810 - 818   2017.5

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    To investigate the items that are considered by physicians when making decisions regarding the resumption of oral intake among patients with aspiration pneumonia who have undergone short-term fasting.We surveyed 2490 Japanese hospitals that had internal m

    DOI： 10.1111/ggi.12792

  • 地域在住者における尿酸値のHbA1cへの影響は男女で異なる

    川本 龍一, 二宮 大輔, 熊木 天児

    糖尿病   60 ( Suppl.1 )   S - 227   2017.4

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  • 地域在住者における握力はメタボリックシンドロームと関係している

    川本 龍一, 二宮 大輔, 笠井 誉久, 千崎 健介, 楠木 智, 大塚 伸之, 熊木 天児

    日本内分泌学会雑誌   92 ( S.Branc )   300   2016.12

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  • Gender difference in preference of specialty as a career choice among Japanese medical students.

    Kawamoto Ryuichi,Ninomiya Daisuke,Kasai Yoshihisa,Kusunoki Tomo,Ohtsuka Nobuyuki,Kumagi Teru,Abe Masanori

    BMC medical education   16 ( 1 )   288   2016.11

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    In Japan, the absolute deficiency of doctors and maldistribution of doctors by specialty is a significant problem in the Japanese health care system. The purpose of this study was to investigate the factors contributing to specialty preference in career c

    DOI： 10.1186/s12909-016-0811-1

  • Handgrip Strength Is Positively Associated with Mildly Elevated Serum Bilirubin Levels among Community-Dwelling Adults.

    Kawamoto Ryuichi,Ninomiya Daisuke,Kumagi Teru

    The Tohoku journal of experimental medicine   240 ( 3 )   221 - 226   2016.11

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    Handgrip strength (HGS) is a useful measure of health-related quality of life and general muscle strength. Serum total bilirubin (T-B) may present potential beneficial effects in preventing oxidative changes which are associated with a risk of metabolic s

    DOI： 10.1620/tjem.240.221

  • 高齢者における疾患に対する重篤感の認識とライフスタイル実現が主観的健康感や幸福感に及ぼす影響について

    柳原 千秋, 二宮 大輔, 熊木 天児, 阿部 雅則, 楠木 智, 川本 龍一

    日本老年医学会雑誌   53 ( 4 )   462   2016.10

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  • 地域在住者における握力はメタボリックシンドロームと関係している

    川本 龍一, 二宮 大輔, 楠木 智, 熊木 天児, 阿部 雅則

    日本老年医学会雑誌   53 ( 4 )   461 - 462   2016.10

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